Dr. Clair Crewe received her Ph.D. in 2015 at the University of Oklahoma Health Sciences Center in Biochemistry and Molecular Biology in the Lab of Luke Szweda. Her doctoral work defined the initiating events in the development of cardiac metabolic inflexibility during high fat feeding in mice. She did her postdoctoral training in the lab of Dr. Philipp Scherer at the University of Texas Southwestern Medical Center in Dallas. During her postdoctoral training Clair studied extracellular vesicles (EVs) in adipose tissue biology. Dr. Crewe is currently an Assistant Professor at Washington University School of Medicine in St. Louis. A focus area of her research is to understand the metabolic consequences of EV-mediated signaling in adaptive and mal-adaptive expansion of adipose tissue in obesity. Dr. Crewe’s work also seeks to understand and manipulate the EV-based signals between energetically stressed adipocytes and other organ systems to improve systemic lipid and glucose metabolism in type 2 diabetes.