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Emilija Šipailaitė 

Researcher, Lithuanian University of Health Sciences, Kaunas, Lithuania
Emilija Šipailaitė work at Lithuanian University of Health Sciences. She has a Pharmacy Master’s degree. She has carried out research in the cell culture laboratory for the last 3 years. During that period, she had a chance to work with many different cell cultures: human skin cells, stem cells and various cancerous cells. She has experience working with exosomes from stem cells and NT2 Parkinson’s disease cybrids. Also, She took part in education programme “Basics to Work With Extracellular Vesicles” in the Institute of Biomedicine and Traslational medicine (MVBS.TK.013), 26 hours (1 ECTS). In addition, in the summer of 2021 I had an ERASMUS+ traineeship “Exosome signaling in bidirectional Microglia - Neuron communication” in University of Coimbra, Portugal. Recently, her  field of interest is plant extracellular vesicles of plants and their effect to human cells.​


Investigation of cucumber extracellular vesicles and their bioactivity on

​human skin cells

Plant-derived extracellular vesicles (EVs) are a novel research subject because of their potential to be used in improving and functionalization of biopharmaceutical delivery. EVs are attractive delivery systems due to their ability to increase stability, solubility, and bioavailability of active agents of the plant. This study aimed to evaluate cucumber EV bioactivity on human skin cells. Fluorescence microscopy confirmed the internalization of plant-derived EVs into the human skin cells after 24 hours. PrestoBlue™ metabolic cell assay revealed that EVs from cucumber fruits significantly increase proliferation of keratinocytes (HaCaT) and fibroblasts (HDF) after 48 hours. Moreover, the EVs shortened wound healing time in in vitro skin model. Therefore, EVs isolated from cucumber can be applied for development of regenerative cosmeceutical and medicinal products.

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​This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 857418.
  • Home
    • About us
    • Combivet Ethics Committee
    • Contact
  • Team
  • Research
    • ​Host-Pathogen Interactions and Disease Biomarkers Discovery >
      • Research project I
      • Research project II
    • Infertility and Subfertility >
      • Research project III
      • Research project IV
      • Research project V
    • ​Food, Feed & Health >
      • Research project VI
    • Non - Communicable Diseases and Cancer >
      • Research project VII
      • Research project VIII
  • Publications
  • NEWS & EVENTS
    • News
    • Seminars
    • Events >
      • Annual conference 2024
      • Research school 2024
      • Ethics debate 2023
      • Research school 2023
      • Annual conference 2023
      • Symposium 2023
      • Conference 2022
      • Summer School 2022
      • One Health Estonia 2022
      • CANLEISH/COMBIVET joint event 2022
  • University of Life Sciences
  • EUP AH&W